Adam Groh
PhD - Neuroscience
Contact
Adam Groh
PhD - Neuroscience
Research interest/program
I am a neuroscientist interested in how non-neuronal cells regulate the integrity of brain borders, and how these specialized interfaces communicate with a changing cerebrospinal fluid (CSF) landscape during development, complex behaviour, and aging/disease. While interactions at the brain's borders sculpt cellular behaviour throughout the central nervous system (CNS), little is known about the brain-wide coordinated activity of these multicellular structures. My research program will target this gap in knowledge by combining cell-resolved sequencing and proteomics, computational modeling and in vivo and in vitro approaches to develop new theories of brain border function that engage with classic theories of how the brain grows, subsists, and responds to complex homeostatic and pathological stimuli.
Background
I received my PhD at the Montreal Neurological Institute-Hospital of McGill University where I was a Tomlinson and Vanier scholar with Dr. Jo Anne Stratton. My doctoral research explored the involvement of ependymal cells in periventricular neuroinflammation, but I also conducted various collaborative investigations focusing on microglia, astrocytes, meningeal fibroblasts, and choroid plexus epithelial cells.
Beyond neurobiology, I enjoy writing about the history of science, which I believe should always inform contemporary work. My most recent article looks at Wilder G. Penfield's studies of glial cells and their influence on modern neuroscience.
Beyond neurobiology, I enjoy writing about the history of science, which I believe should always inform contemporary work. My most recent article looks at Wilder G. Penfield's studies of glial cells and their influence on modern neuroscience.