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Adam Groh
PhD - Neuroscience

adam.groh [at] mail.mcgill.ca


Neurology and Neurosurgery

McGill University

Headshot: Clara Lacasse



Site avatar
Adam Groh
PhD - Neuroscience

Contact
Site avatar
Adam Groh
PhD - Neuroscience

adam.groh [at] mail.mcgill.ca


Neurology and Neurosurgery

McGill University

Headshot: Clara Lacasse




About


Research focus

I am broadly interested in how non-neuronal cells work synergystically to maintain brain homeostasis. In particular, I am fascinated by the dynamic cellular interactions that occur at the brain's borders, namely the ventricular wall, choroid plexuses, and meninges.

I am currently a Human Frontier Science Program (HFSP) Long-Term Fellow in the Department of Physiology, Anatomy and Genetics at the University of Oxford working with Dr. Francis Szele. My research seeks to understand if and how age-associated changes to fluid regulation and glial interactivity in the subventricular zone modify adult neurogenic potential.

My future research program will combine advanced in vivo and in vitro approaches, cell-resolved sequencing and proteomics, and machine learning-informed computational modeling to develop novel glia-centered theories that elucidate how the brain executes specific tasks and responds to varied pathological stimuli. 

Background

I received my PhD at the Montreal Neurological Institute-Hospital of McGill University with Dr. Jo Anne Stratton. My doctoral research explored the involvement of ependymal cells in periventricular neuroinflammation, but I also conducted various collaborative investigations focusing on microglia, astrocytes, meningeal fibroblasts, and choroid plexus epithelial cells. These wide-ranging studies helped establish a strong foundation in glial neurobiology.  
 
As a trained classical pianist, choral singer, and regular 'consumer' of art, I think of science more as the constrained expression of a creative impulse to explain the natural world, rather than a strict method. For this reason, and others, I love to read and write about the history and philosophy of science - a topic that significantly influences how I think and therefore the questions I ask.

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