Adam Groh
PhD - Neuroscience
Contact
Adam Groh
PhD - Neuroscience
Research focus
I am a neuroscientist interested in how non-neuronal cells regulate the integrity of brain borders and how these specialized interfaces communicate with a changing cerebrospinal fluid landscape during development, complex behaviour, and aging/disease. While cellular interactions at the brain's borders sculpt nearby and distal brain activity, little is known about the coordinated interplay of these interfaces in the maintenance of central nervous system (CNS) homeostasis. My research program will target this gap in knowledge by combining cell-resolved sequencing and proteomics, computational modeling and in vivo and in vitro approaches to develop new theories of CNS border function that engage with classic theories of how the brain grows and subsists.
Background
I received my PhD at the Montreal Neurological Institute-Hospital of McGill University where I was a Tomlinson and Vanier scholar with Dr. Jo Anne Stratton. My doctoral research explored the involvement of ependymal cells in periventricular neuroinflammation, but I also conducted various collaborative investigations focusing on microglia, astrocytes, meningeal fibroblasts, and choroid plexus epithelial cells.
I also read and write about the history and philosophy of science - a topic that significantly influences how I think and therefore the questions I ask.
I also read and write about the history and philosophy of science - a topic that significantly influences how I think and therefore the questions I ask.